For neurological and other disorders associated with disturbance of the nerve cell metabolism in which high-dose B-complex vitamins play a role. These include: polyneuritis (of toxic and nontoxic etiology); neuralgias e.g. lumbalgia, trigeminal neuralgia, shoulder-arm syndrome, herpes zoster, cervical syndrome, ischialgia, etc; diabetic neuropathy; metabolic and neurophatic changes due to pregnancy and oral contraceptives, convalescence.